TLDR
- Sanofi launches a €1 billion share buyback program running from February 3 to December 31, 2026
- Q4 2025 operating profit jumped 12.7% to €2.34 billion, with revenue of €11.3 billion beating analyst expectations
- The company forecasts high single-digit sales growth in 2026, powered by immunology and vaccine divisions
- This follows a much larger €5 billion buyback in 2025, including a €3 billion off-market transaction with L’Oréal
- Dupixent remains the top revenue driver, accounting for roughly 30% of total sales
Sanofi has announced plans to buy back up to €1 billion of its own shares throughout 2026. The program kicks off February 3, 2026, and runs through the end of the year.
The French pharmaceutical company has already locked in an agreement with an investment service provider to handle the transactions. The buyback represents about $1.20 billion at current exchange rates.
This latest program comes on the heels of strong fourth-quarter results. Operating profit climbed 12.7% to €2.34 billion in Q4 2025. Revenue hit €11.3 billion, topping what analysts had projected.
Earnings per share of €1.53 beat expectations by €0.06. The company’s gross margin stands at 71.32%, while the operating margin reached 21.82%.
For 2026, Sanofi is projecting high single-digit sales growth. The company expects momentum to continue in its core immunology and vaccine businesses.
Dupixent remains the star performer in Sanofi’s portfolio. The drug pulls in approximately 30% of the company’s total sales. It’s the clear revenue leader among all Sanofi products.
Following a Massive 2025 Buyback
The new €1 billion program follows an even bigger initiative from 2025. Last year, Sanofi completed a €5 billion share repurchase.
That 2025 program included a €3 billion off-market block trade. The transaction involved buying back shares from L’Oréal, a long-time shareholder in the company.
Share buybacks reduce the number of shares trading in the market. This can boost earnings per share even if total profits stay the same. It’s a common way companies return cash to investors.
The move also sends a message about management’s confidence. Buybacks typically signal that executives believe their stock is undervalued or that the business is in good shape.
Sanofi is reshaping its business structure while executing these buybacks. The company is spinning off its consumer health unit to sharpen focus on higher-growth areas.
Strategic Shift and Market Position
Sanofi is concentrating more resources on immunology, vaccines, and rare diseases. These areas offer stronger growth potential than traditional consumer health products.
The company generates about 45% of revenue from the United States. Europe accounts for roughly 20% of sales, while China brings in 6%.
Sanofi operates with a current ratio of 1.09 and a debt-to-equity ratio of 0.29. These numbers point to a balanced capital structure.
The company reported 3-year revenue growth of 4.2%. This steady expansion backs up management’s decision to return capital to shareholders.
Wall Street analysts give the stock a Moderate Buy rating. Two analysts recommend buying, while three suggest holding.
The average price target sits at $79.18, suggesting 67.51% upside from current levels. The company’s market capitalization stands at €114.17 billion.
Institutional investors hold 9.96% of Sanofi shares. The stock’s P/E ratio of 11.52 and P/S ratio of 2.17 trade near historical lows.
Sanofi has signed the formal agreement to execute the €1 billion buyback and will begin repurchasing shares on February 3, 2026.




