October has a way of changing the energy of the crypto market – traders even gave it a nickname: “Uptober.” Bitcoin tends to post some of its strongest monthly gains here, and this year has already delivered a new all-time high above $125,000.
When BTC rallies, liquidity spreads across the market. That’s usually how altseasons kick in – capital flows down the risk ladder, producing faster moves in smaller caps while everyone’s still focused on Bitcoin.
Meme coins do exceptionally well in this kind of environment. They run on speculative energy, move quickly when narratives take off, and their smaller valuations mean even modest buying pressure can send their prices flying. That makes them attractive when sentiment shifts bullish.
With Uptober in full swing, we’ve put together five picks that could rally hard. Here’s our shortlist of the best meme coins to buy – each with the potential to 100x this month.
1. Maxi Doge (MAXI)
Maxi Doge (MAXI) is undoubtedly one of the best meme coins to buy during this Uptober rally. Unlike Dogecoin, which already boasts a $39 billion market cap, MAXI offers a micro-cap entry point while still delivering a full dog coin identity.
The project aligns with the “degen” trader vibe and supports it with actual features, including staking (122% APY) and weekly trading competitions with crypto prizes. There are even plans to offer MAXI futures with up to 1,000x leverage.
Right now, Maxi Doge is still in presale at $0.000261 per token and has raised over $2.9 million, with around $100,000 rolling in daily. Smart money is paying attention, and analysts like Alessandro De Crypto are now calling MAXI the “next Dogecoin.”
Time will tell whether Maxi Doge can live up to the hype. But with lots of early traction and multiple audits completed, this looks like one of Uptober’s breakout meme coin plays. Visit Maxi Doge Presale.
2. PEPENODE (PEPENODE)
PEPENODE (PEPENODE) has been getting attention this Uptober as one of the hottest pre-launch meme coins. It capitalizes on the broader frog coin theme but adds utility with a “Mine-to-Earn” system that separates it from its peers.
Instead of just holding PEPENODE, you can buy virtual Miner Nodes, build out server rooms, and generate crypto rewards – no hardware, no electricity bills, and no GPUs required. Every Miner Node upgrade burns 70% of the tokens used, creating steady deflationary pressure that could boost PEPENODE’s price.
The ongoing presale has already raised $1.7 million, and early investors can buy PEPENODE tokens for just $0.0010918 each. Plus, presale investors can immediately stake their PEPENODE for 753% APY.
Frog-themed meme coins historically pump when Pepe rallies. And given that the OG frog coin is up 7% in the past week alone, now might be the perfect window to get involved in the PEPENODE presale. Visit PEPENODE Presale.
3. SKYAI (SKYAI)
SKYAI (SKYAI) is a BNB Smart Chain project that combines meme culture with AI infrastructure. Its main selling point is the Model Context Protocol (MCP), which allows developers to build on-chain AI agents for tasks such as contract audits, token tracing, and cross-chain analytics.
The project first made noise back in April when its Four.meme presale raised $50 million in just 36 hours, setting a record on the BNB Chain. That momentum carried over into live trading, with SKYAI now sitting at $0.033 and generating over $37 million in spot trading volume since yesterday.
It’s up over 32% in the last week, and community sentiment on CoinMarketCap is 79% bullish. Of course, volatility is expected given its low market cap, but as a “meme coin with brains,” SKYAI might be one of the more intriguing options on our list.
4. Giggle Fund (GIGGLE)
Giggle Fund (GIGGLE) is taking a different approach with a charity-first model. Built on the BNB Smart Chain, every buy and sell triggers a 5% tax, with half of the proceeds donated to charity. In just a few weeks since launch, that setup has generated over $8.7 million in donations.
GIGGLE’s tokenomics are simple – a one-million token supply and no minting. Trading has been explosive this week, with $45 million in 24-hour spot volume and a market cap that hit $117 million yesterday.
What’s also fueling the buzz is Binance founder CZ openly supporting it, calling Giggle Fund the first meme coin with “real utility.” So, with Tier-1 CEX listing rumors heating up, GIGGLE looks like another of the best meme coins to buy in Uptober.
5. Bitcoin Hyper (HYPER)
Bitcoin Hyper (HYPER) is unique – its pitch stretches beyond internet memes. It’s a Bitcoin Layer-2 network combining Solana-like performance with Bitcoin’s security, aiming to unlock new use cases for the world’s largest crypto.
Because it integrates the Solana Virtual Machine (SVM), developers can build high-speed, Rust-based apps on Bitcoin. Within this Layer-2 ecosystem, wrapped BTC serves as the transaction currency, providing it with multiple use cases.
Investors are excited. The HYPER token presale has raised $22 million to date, with multiple whale purchases made in recent days. Early buyers can also stake for yields of 55% per year, providing a way to earn more HYPER ahead of the official launch.
Looking ahead, Bitcoin Hyper’s team has a roadmap that lays out plans for developer grants and DAO governance. If they can keep this early momentum going, HYPER might be capable of producing 100x (or more) returns once it hits exchanges. Visit Bitcoin Hyper Presale.
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